DEF8 and Alzheimer disease: These 439 risk genes encompass well‐established (“canonical”) AD genes, i.e., Abi3, Apoe, Bin1, Clu, Def8, Epha1, Fcer1 g, Fermt2, H2‐Ab1 (HLA‐DQA in humans), Inpp5d, Plcg2, Prss36, Rin3, Siglech (CD33 in humans), Spi1, Tomm40, Trem2, and Zcwpw1. The 421 other genes in this data set have been associated to AD with decreasing degrees of statistical certainty.