APOE and dementia: In multivariable Cox‐proportional hazards regression models adjusted for demographics, vascular risk factors, use of lipid‐lowering therapies and ApoE4 carrier status, the ratio of ceramides C24:0/C16:0 was inversely associated with incident dementia (Hazards ratio [HR] per each standard deviation [SD] increment 0.73, 95% CI 0.56–0.96, P = 0.023) and AD dementia (HR 0.73, 95% CI 0.53–1.00, P = 0.050).