After adjustment for sex and age, the association of the kidney disease patient and serum CN-1 slightly weakened and was no longer significant (β = −0.219, p = 0.089) (model 1), but the association became uncovered again by further adjustment for urinary CN-1 concentrations (β = −0.281, p = 0.033) (model 2) (Supplementary ). Here, CNDP1 is linked to kidney disorder.