However, the initial steps of fatty acid biosynthesis were not significantly altered during infection, as demonstrated by the protein levels of phosphorylated ATP-citrate lyase (pACL), acetyl CoA-synthase (AceCS1), and phosphorylated acetyl co A carboxylase (p-ACC) in the livers of RD-fed mice compared to uninfected RD-fed mice (Figures 2(a), 2(c), 2(d), and 2(e)). The gene discussed is ACLY; the disease is infection.