CD274 and non-small cell lung carcinoma: In addition, our study demonstrated for the first time that, for NSCLC patients at relatively early stage (I-III) without prior therapy, the concordance rate for PD-L1 expression in primary and metastatic NSCLC is higher compared with those for the stage IV patients (81.3% vs 71.4%, 100% vs 85.7% at 1% and 50% threshold, respectively).