CD274 and neoplasm: If 50% TPS is used as a threshold, 14/103 (13.6%) of the metastatic lesions had inconsistent PD-L1 expression compared to the primary tumor tissue (k = 0.53, and P < 0.001), among which, 10 (9.7%) cases had reduced PD-L1 expression and 4 (3.9%) case had increased PD-L1 expression in the metastasis lesions.