CD274 and neoplasm: If 1% TPS was used as a threshold, 28/103 (27.2%) of the metastatic lesions had inconsistent PD-L1 expression compared to the primary tumor tissue (k = 0.46, and P < 0.001), among which, 24 (23.3%) cases had reduced PD-L1 expression and 4 (3.9%) case had increased PD-L1 expression in the metastasis lesions.