Those related studies that had be conducted before had shown that the expression of p53 [also known as tumor protein p53 (TP53)], p21 [cyclin dependent kinase inhibitor 1A (CDKN1A)], nm23 [also known as nucleoside diphosphate kinase 1 (NME1)] and VEGF [also known as vascular endothelial growth factor A (VEGFA)] could reflect the prognosis of liver cancer by immunohistochemical techniques 11-14. This evidence concerns the gene CDKN1A and liver cancer.