It has been reported that RACK1 plays as an oncogene in various tumor types , such as prostate cancer 14, ovarian cancer 15, esophageal squamous cell carcinoma 16, glioma 17, nasopharyngeal carcinoma 18, oral squamous-cell carcinoma (OSCC) 19, breast cancer 20, esophageal carcinoma 21, acute promyelocytic leukemia 22, myeloma 23, colorectal carcinoma 24, 25, non-small cell lung cancer 26, 27, hepatocellular carcinoma (HCC) 28, 29, and etc. This evidence concerns the gene RACK1 and Familial prostate cancer.