TNF and cancer: pathways in cancer (p value = 7.7 ∗ 10(−12), hsa05200, degree = 28), PI3K-Akt signaling pathway (p value = 1.0 ∗ 10(−5), hsa04151, degree = 18), MicroRNAs in cancer (p value = 1.0 ∗ 10(−3), hsa05206, degree = 13), Proteoglycans in cancer (p value = 7.2 ∗ 10(−4), hsa05205, degree = 11), and TNF signaling pathway (p value = 1.7 ∗ 10(−4), hsa04668, degree = 9) may be crucial pathways.