Likely, diverse experiments demonstrated that AVP in pregnancy is sufficient to up-regulate the expression of the co-stimulatory molecules CD80, CD86, and major histocompatibility complex class II (CLII) on dendritic cells23, which are necessary in the early pathogenesis of MS and EAE7 and induce a pro-inflammatory Th1 and Th17 profile, with elevated IFN-γ and IL-1723. The gene discussed is CD80; the disease is myeloid sarcoma.