We found increased expression of the KDELR3-001 transcript, but interestingly not the alternate transcript, KDELR3-002, in late-stage (stages III and IV) metastatic melanoma patients compared with early-stage (stages I and II) melanoma patients (Fig. 6a), consistent with a role for KDELR3 in melanoma progression. The gene discussed is KDELR3; the disease is melanoma.