NUDT9 and Miyoshi myopathy: According to GO enrichment analysis by target miRNAs, the target miRNAs of dysregulated circRNAs in MM were enriched in biological processes (e.g. positive regulation of t cell mediated cytotoxicity and synaptonemal complex assembly), cellular components (e.g. high density lipoprotein particle and MHC class I protein complex), and molecular functions (e.g. adp ribose diphosphatase activities and endodeoxynuclease activity produci) (Fig. 3c).