GO enrichment analysis by located genes revealed that the located genes of dysregulated circRNAs in MM were enriched in biological processes (e.g. positive regulation of cytoplasmic mRNA and cellular response to hypoxia), cellular components (e.g. cytosol and membrane), molecular functions (e.g. protein binding and protein kinase activity) (Fig. 3a). Here, WEE1 is linked to Miyoshi myopathy.