And circ-AFF2 (AUC: 0.757, 95% CI: 0.641–0.872), circ-WWC3 (AUC: 0.773, 95% CI: 0.673–0.874), circ-DNAJC5 (AUC: 0.672, 95% CI: 0.557–0.787), circ-KLHL2 (AUC: 0.677, 95% CI: 0.564–0.790), circ-IQJAP1 (AUC: 0.758, 95% CI: 0.655–0.860), circ-AL137655 (AUC: 0.708, 95% CI: 0.601–0.816) could predict lower MM risk. Here, KLHL2 is linked to Miyoshi myopathy.