Important miRNAs involved in the cardiac hypertrophy are also miRNA-22 (influence phosphatidylinositol-3-kinase (PI3K)-protein kinase B (AKT)) [100], miRNA-212/132 family (active through antihypertrophic FoxO3 transcription factor), or miRNA-199 (miRNA-199a targets the pro-autophagic and antihypertrophic factor glycogen synthase kinase 3β; miRNA-199b acts through targeting tyrosine phosphorylation regulated kinase 1A (Dyrk1a) gene, involved in the phosphorylation of NFAT factors) [101,102,103]. The gene discussed is AKT1; the disease is cardiac hypertrophy.