Several genes responsible for DCM, including MYH7, TNNT2, LMNA, DES, TTN, PLN, ACTC1, SCN5A, NKX2-5 and TBX5, have been identified for clinical diagnosis and evaluation of genetic susceptibility [4,5,6]. The gene discussed is NKX2-5; the disease is familial dilated cardiomyopathy.