SREBF1 and hydrops fetalis: Specifically, choline supplemented fetuses had lower hepatic mRNA expression of acetyl-CoA carboxylase 1 (Acc1), fatty acid desaturase 1 (Fads1), and ELOVL fatty acid elongase 5 (Elovl5), as well as sterol regulatory element-binding transcription factor 1 (Srebf1), which activates the transcription of lipogenic genes, when compared to unsupplemented HF fetuses [5].