A similar approach was pursued by Cantisani et al. who, using a siRNA library targeting the human kinome and related proteins, identified genes belonging to the EPH (ephirin) receptor tyrosine kinase, SRC (SRC proto-oncogene, non-receptor tyrosine kinase), and MAPK (mitogen activated protein kinase) families as necessary for the viability of thyroid tumor cells, but not for normal cells, and proposed them as potential novel therapeutic targets for thyroid tumors [77]. Here, SRC is linked to thyroid tumor.