GDF3 levels showed stronger predictive capacity with AUC value of 0.770 (95% CI, 0.593-0.947, p = 0.033), when compared to other conventional sepsis biomarkers (i.e., lactate (Lac), C-reaction protein (CRP), procalcitonin (PCT) and serum amyloid A (SAA)) (Figure 1F and Supplementary Table S3). The gene discussed is CRP; the disease is Sepsis.