Figure 2B demonstrates a representative CK20 IHC staining in MCC. Representative YTHDF1high and YTHDF1low MCC are shown in the right and middle panels of Figure 2B. Analysis of survival data available in our cohort of MCC patients revealed worse overall survival in YTHDF1high MCC patients compared to YTHDF1low patients (log-rank p value = 0.045) (Figure 2C and Figure S1D). This evidence concerns the gene KRT20 and Merkel cell skin cancer.