As shown in Table 3, there were no significant differences between the high and low N-cadherin expression groups in terms of clinicopathological factors including age, tumor size, nuclear grade, venous involvement, lymphatic involvement, lymph node metastasis, ER/PgR/HER2 status, and subtype. The gene discussed is ESR1; the disease is metastatic malignant neoplasm in the lymph nodes.