The NRG1 gene is the susceptible gene of schizophrenia.19 We discussed the role of NRG1 gene in the patients with HCC complicated with PTSD, and it was found that compared to the control group, there was no significant difference in the NRG1 level in patients in the HCC group (P > .05), while significant decreased NRG1 level was found in patients in the HCC + PTSD group (P < .05; Figure 1B). The gene discussed is NRG1; the disease is post-traumatic stress disorder.