CASC9 accelerated ovarian cancer cell proliferation, invasion, and migration via acting as a competing endogenous RNA (ceRNA) for miR‐758‐3p to modulate LIN7A expression.21 CASC9 enhanced breast cancer cell proliferation and metastasis through positively regulating CHK1 via sponging the miR‐195/497 cluster 32 or through miR‐215/TWIST2 signaling.18 Elevated CASC9 promoted oral squamous cell carcinoma progression by inhibiting autophagy‐mediated apoptosis.20 However, the influence of CASC9 in PTC remains enigmatic. Here, TWIST2 is linked to oral cavity squamous cell carcinoma.