Cervical cancer cells express TLR3 and are therefore one of the target cells of poly(I:C).14 We examined the cytokine expression profiles of two different HPV‐positive cervical cancer cells, HeLa (HPV18+) and Caski (HPV16+), and found that both cervical cancer cells highly expressed IL‐6, which is consistent with previous studies.15 Moreover, after the poly(I:C) treatment, the expression of IL‐6 in these two cervical cancer cell lines was rapidly up‐regulated within 12 hours of poly(I:C) treatment and remained stable for 48 hours. This evidence concerns the gene TLR3 and cervical cancer.