We used an RT112 bladder cancer cell line knocked down for endogenous MRE11 and re-expressing an MRE11 construct containing either the full length MRE11 coding sequence (MRE11 isoform 1) or the MRE11 coding sequence lacking MRE11 exon 16 (MRE11 isoform 2). This evidence concerns the gene MRE11 and urinary bladder cancer.