CD8A and cancer: To our expectation, compared to the other two cancer types, endometroid EC has significantly higher level of cytotoxic immune cells, including CD8 T cells and NK cells, and also Treg cells, whose function is to constrain CD8T cells in tumor (Mougiakakos et al., 2010) (adjusted p value  < 0.05, Student’s t-test, Fig. 5C).