The results showed that the expression of ITK, EBI3, CX3CL1, MYC, EOMES, CA4, TAGAP, MMP2, HAVCR2, FCGR1 and SNAI2 were not only associated with early recurrence of GC after sugery, but also with the short DFS time. The gene discussed is HAVCR2; the disease is gastric cancer.