And the consumption of EPB41L4A-AS1 in tumor treatment can increase the sensitivity of tumors to glutaminase inhibitors.32 2) EPB41L4A-AS1 plays an important role in the diagnosis and prognosis evaluation of various cancers including cervical cancer, liver cancer, breast cancer, bladder cancer, glioblastoma, and colorectal cancer.33-35 That is, the low expression of EPB41L4A-AS1 is associated with a low survival rate of these cancer types. This evidence concerns the gene GLS and cancer.