Comparison of survival curves displayed that no apparent difference was found between Low STAT3 patients who had less STAT3 mRNA expression in HCC tissues and High STAT3 patients with more STAT3 mRNA in HCC tissues compared to adjacent liver tissues (HR = 0.98, P = 0.93, Supplementary Fig 2B). The gene discussed is STAT3; the disease is hepatocellular carcinoma.