GLI2 and central nervous system cancer: Hh signalling plays an important role in embryogenesis, stem-cell renewal, and EMT.52 The glioma-associated oncogene family, which includes GLI2, are the master transcriptional regulators of Hh signaling.53,54 We therefore revisited the RNA sequencing data to identify other genes that contribute to the stem-like phenotype associated with IPA Network 1.