CD40LG and neoplasm: In line with that, incubation of irradiated CFPAC-1 tumour-loaded autologous PBMCs with CFPAC-1 tumour specific CD3 + CD8+ T cells in response to CFPAC-1-tumour lysate-loaded mCD40L- activated DC stimulated CD3 + CD8+ T cells cytotoxic response and resulted in higher percentage of CD3 + CD8+ T cells with positive staining for IFN-γ and CD107a compared to those CFPAC-1 tumour specific CD3 + CD8+ T cells generated in response to CFPAC-1-tumour lysate-loaded DC activated through other treatments including sCD40L and MC.