Nicotinamide adenine dinucleotide-cytochrome c reductase (NCCR), succinate-cytochrome c reductase (SCCR), and cytochrome c oxidase (CCO) activities of the P group were all significantly lower compared to those of the C group (p < 0.05), which revealed that mitochondrial function in the prostate was downregulated in rats with prostatic hyperplasia. The gene discussed is RYR1; the disease is benign prostatic hyperplasia.