The MM.1 S cells were reduced to below detectable levels by single injections of CAR T cells expressing each of the anti-BCMA CARs assessed: 11D5-3-CD8BBZ, FHVH33-CD828Z, and FHVH33-CD8BBZ; however, most mice receiving FHVH33-CD828Z-expressing T cells developed high-tumor-burden relapses (Fig. 6a, numerical bioluminescence comparisons are in Supplementary Fig. 13). This evidence concerns the gene TNFRSF17 and neoplasm.