In a recent study performed in Japan, was reported that patients with MEFV exon 10 mutations showed earlier onset of the disease and frequently showed serositis, whereas the patients with the absence of MEFV exon 10 mutations showed later onset of FMF, with musculoskeletal manifestations as arthritis, myalgia, and erysipelas-like erythema [11]. The gene discussed is MEFV; the disease is familial Mediterranean fever.