Furthermore, the increased expression of KDM2B was positively associated with poorer tumor differentiation (Fig. 6f, g, h and Additional file 3: Table S3), lymph nodes metastasis (Fig. 6i, j, k and Additional file 3: Table S3) and higher TNM stages (P = 0.001; Additional file 3: Table S3). The gene discussed is KDM2B; the disease is neoplasm.