SGMS1 and cancer: To assess the impact of MOB1 expression on PDAC cancer cell biology, we transfected PANC-1 and AsPC-1 cells, which had very low or intermediate levels of endogenous MOB1, with pcDNA3.0/HA-tagged MOB1 (PANC-1/AsPC-1-pMOB1), and pcDNA3.0 was used as control (Fig. 2a).