Similarly, LINC01234 acted as a ceRNA of miR-642a-5p, resulting in the suppression of the endogenous serine hydroxymethyl transferase 2 (SHMT2), suggesting that the LINC01234-miR642a-5p-SHMT2 axis plays a key role in colon cancer [42]. Here, SHMT2 is linked to malignant colon neoplasm.