From the FDA-approved tests, urinary cytology, nuclear matrix protein 22 (NMP22) kit, NMP22 BladderChek Test, BTA-TRAK and BTA stat kits, Cell Search, and UroVysion are approved for initial detection and surveillance of BC whereas some tests, such as uCyt +, are only approved for the follow-up of BC [43]. Here, NUMA1 is linked to breast cancer.