ABCG2 and colonic neoplasm: Similarly, we found that the ABCG2-overexpressing human S1-M1-80 colon cancer cells (Figure 1c) and the ABCG2-overexpressing human H460-MX20 lung cancer cells (Figure 1d) are equally sensitive to sitravatinib as their parental S1 and H460 cancer cells, respectively.