Through further detection of the NLRP3 inflammasome in the tumor tissue of A549-bearing athymic nude mice using Western blotting and immunohistochemistry methods, Figure 1B showed that PPVI significantly improved the protein expression of NLRP3, cleaved-caspase-1, cleaved-IL-1β and cleaved-GSDMD in tumor tissue. This evidence concerns the gene NLRP3 and neoplasm.