PIR and colorectal carcinoma: Consequently, we also profiled the expression of piR-24000 in 20 distant liver metastases and found a strong overexpression of this piRNA in liver metastases as compared to non-metastatic CRC tissues (median: −11.79 vs. −13.53, p = 0.0023) as well as to the normal colonic mucosa (median: −11.79 vs. −15.72, p < 0.0001).