Maternal plasma TNF-α levels were significantly higher according to GDM (GDM: 0.86 ± 0.35 pg/mL vs. NGT: 0.32 ± 0.35 pg/mL, P < 0.0001), this significance continued after adjusting for BMI (Prepregnancy BMI: P = 0.0001, BMI at delivery: P = 0.0001). This evidence concerns the gene TNF and gestational diabetes.