The patients who developed AKI were characterized by more pronounced laboratory abnormalities during the first two days of hospital stay: lower hematocrit, higher CRP, higher D-dimer, angiopoietin-2 and sFlt-1 as well as higher results of laboratory tests associated with renal function (serum urea, creatinine, cystatin C and BTP, serum and urine NGAL) (Table 1). The gene discussed is CST3; the disease is acute kidney injury.