Our recent studies showed that aberrant expression of lncRNA H19 not only contributed to the bile duct ligation (BDL) and carbon tetrachloride (CCl4) and multidrug resistance 2 (Mdr2) deficiency-induced fibrotic liver injury but also was associated with disease progression in human PSC, PBC, and biliary atresia patients [8,9,10]. Here, ABCB4 is linked to primary biliary cholangitis.