PIK3CG and bacterial infectious disease: To our knowledge, we demonstrate for the first time that PM10 exposure followed by an oxidant stimulus with H2O2 upregulates the pAKTSer473/pAKTThr308/pFoxO3aSer253, with a reduction in apoptosis mediated by PI3K in lung epithelial cells, which could mimic air pollutants exposure followed by oxidant endogenous stimulus seen, for instance, during bacterial infections.