In an interesting study conducted by Chong et al., targeted sequencing of MYC, BCL2, BCL6 and the immunoglobulin (IG) loci was applied in 112 DLBCL cases with a MYC aberration to explore the rearrangement at base pair resolution and to identify the partner gene identity [87]. The gene discussed is MYC; the disease is diffuse large B-cell lymphoma.