MMP11 and metastatic malignant neoplasm in the lymph nodes: Furthermore, carriers who possess at least one C allele (C/T + C/C genotype) of the MMP11 SNP rs738792 were more likely to develop Child-Pugh B or C grade, while individuals who carried (C/T + C/C genotype) at the MMP11 SNP rs28382575 were observed to have higher risk to develop large tumors, lymph node metastasis or stage III/IV disease [38].