AFP and neoplasm: A >10% reduction of AFP (ORR: 63.6% vs. 10.2%, p < 0.001; DCR: 81.8% vs. 14.3%, p < 0.001) performed a better discriminative ability in tumor response than AFP reduction >20% (ORR: 64.7% vs. 14.8%, p < 0.001; DCR: 82.4% vs. 20.4%, p < 0.001) or >30% (ORR: 61.5% vs. 19.0%, p = 0.001; DCR: 84.6% vs. 24.1%, p < 0.001).