TG and hypothyroidism: Fig 6A shows the GATA2/GAPDH ratio (y-axis) in a linear scale and T3 (x-axis) in a log scale, this is the reverse of that seen in clinical situation, i.e., TSH in a log scale and thyroid hormones in a linear scale [21–23, 24]. However, strong repression of GATA2/GAPDH ratio by T3 was observed when both are plotted in a linear scale (Fig 6B). Furthermore, potent suppression was found even when the GATA2/GAPDH ratio and T3 were plotted in a log scale and linear scale, respectively (Fig 6C), especially at the T3 concentration those observed in moderate hypothyroidism and euthyroidism [57].