Mocchetti et al. found that fibroblast growth factor receptor (FGFR) 2 was frequently expressed in hepatoma-derived cell lines while healthy human primary hepatocytes did not express FGFR2; his group proposed that HCC proliferation might be regulated through autocrine or paracrine mechanisms mediated by FGF/FGFR2 [12]. Here, FGFR2 is linked to hepatocellular carcinoma.