The research of KRAS and NRAS (RAS genes) mutations is highly important since the existence of a mutation on codons 12, 13, 59, 61, 117 or 146 is known as a resistance marker to anti-EGFR monoclonal antibodies (i. e. cetuximab and panitumumab) associated with chemotherapy in the management of patients with metastatic colorectal cancer (mCRC) [6]. Here, NRAS is linked to metastatic colorectal cancer.