Cells expressing WT p21 3'-UTR showed significantly reduced expression in the presence of the miR301a-3p mimic compared to the scrambled miRNA mimic but had little effect on the luciferase activity of mutant p21 3'-UTR mut1 and mut2 in both oral cancer cell lines (Figs5GandS5F). Here, CDKN1A is linked to lip and oral cavity carcinoma.