CRP and Sepsis: A further ICU study by Andaluz-Ojeda et al. [2] in 326 patients with severe sepsis or septic shock, as well as that of Enguix-Armada [30] in 388 patients with septic shock, also found MR-proADM to have the highest predictive value compared to conventional biomarkers such as PCT, CRP and lactate, although interestingly, the greatest performance was found in patients with a lower degree of organ failure.