KLK3 and posterior cortical atrophy: In contrast, men with baseline PSA levels of 2.00 to 2.99 ng/mL, 3.00 to 3.99 ng/mL, and especially 4.00 ng/mL or greater had 13-year actuarial risks of a clinically significant PCa diagnosis of 10.6%, 15.3%, and 29.5%, respectively.